The shift to cloud adoption and hybrid work has revolutionized digital operations but complicated visibility, compliance, and security. Secure access service edge (SASE) centralizes protection for distributed environments, with CASB playing a key role. To support SASE, CASB must evolve to enhance Zero Trust, detect misconfigurations, prevent data leakage, and block sophisticated attacks. Palo Alto Networks' Next-Generation CASB, part of Prisma Access, secures SaaS access, applications, and data against emerging threats.